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Sinusitis; Prepared by: Office of Communications and Public Liaison National
Institute of Allergy and Infectious Diseases National Institutes of Health Bethesda,
MD 20892
What is sinusitis?
You're coughing and sneezing and tired and achy.
You think that you might be getting a cold.
Later, when the medicines you've been taking to relieve the symptoms of the
common cold are not working and you've now got a terrible headache, you finally
drag yourself to the doctor. After listening to your history of symptoms, examining
your face and forehead, and perhaps doing a sinus X-ray, the doctor says you
have sinusitis.
Sinusitis simply means your sinuses are infected or inflamed, but this gives
little indication of the misery and pain this condition can cause.
Health care experts usually divide sinusitis cases into Acute, which lasts
for 3 weeks or less Chronic, which usually lasts for 3 to 8 weeks but can continue
for months or even years Recurrent, which is several acute attacks within a
year Health care experts estimate that 37 million Americans are affected by
sinusitis every year.
Health care workers report 33 million cases of chronic sinusitis to the U.S.
Centers for Disease Control and Prevention annually. Americans spend millions
of dollars each year for medications that promise relief from their sinus symptoms.
What are sinuses?
Sinuses are hollow air spaces in the human body.
When people say, "I'm having a sinus attack," they usually are referring to
symptoms in one or more of four pairs of cavities, or sinuses, known as paranasal
sinuses. These cavities, located within the skull or bones of the head surrounding
the nose, include the: Frontal sinuses over the eyes in the brow area Maxillary
sinuses inside each cheekbone Ethmoid sinuses just behind the bridge of the
nose and between the eyes Sphenoid sinuses behind the ethmoids in the upper
region of the nose and behind the eyes
Each sinus has an opening into the nose for the free exchange of air and mucus,
and each is joined with the nasal passages by a continuous mucous membrane lining.
Therefore, anything that causes a swelling in the nose-an infection, an allergic
reaction, or an immune reaction-also can affect the sinuses. Air trapped within
a blocked sinus, along with pus or other secretions, may cause pressure on the
sinus wall. The result is the sometimes intense pain of a sinus attack. Similarly,
when air is prevented from entering a paranasal sinus by a swollen membrane
at the opening, a vacuum can be created that also causes pain.
What are the symptoms of sinusitis?
The location of your sinus pain depends on which sinus is affected.
Headache when you wake up in the morning is typical of a sinus problem. Pain
when your forehead over the frontal sinuses is touched may indicate that your
frontal sinuses are inflammed.
Infection in the maxillary sinuses can cause your upper jaw and teeth to ache
and your cheeks to become tender to the touch.
Since the ethmoid sinuses are near the tear ducts in the corner of the eyes,
inflammation of these cavities often causes swelling of the eyelids and tissues
around your eyes, and pain between your eyes.
Ethmoid inflammation also can cause tenderness when the sides of your nose are
touched, a loss of smell, and a stuffy nose. Although the sphenoid sinuses are
less frequently affected, infection in this area can cause earaches, neck pain,
and deep aching at the top of your head. Most people with sinusitis, however,
have pain or tenderness in several locations, and their symptoms usually do
not clearly indicate which sinuses are inflamed.
Other symptoms of sinusitis can include Fever, Weakness, Tiredness, a cough
that may be more severe at night, runny nose (rhinitis) or nasal congestion.
In addition, the drainage of mucus from the sphenoids or other sinuses down
the back of your throat (postnasal drip) can cause you to have a sore throat.
Mucus drainage also can irritate the membranes lining your larynx (upper windpipe).
Not everyone with these symptoms, however, has sinusitis. On rare occasions,
acute sinusitis can result in brain infection and other serious complications.
What are some causes of acute sinusitis?
Most cases of acute sinusitis start with a common cold, which is caused by a
virus. These viral colds do not cause symptoms of sinusitis, but they do inflame
the sinuses. Both the cold and the sinus inflammation usually go away without
treatment in 2 weeks. The inflammation, however, might explain why having a
cold increases your likelihood of developing acute sinusitis.
For example, your nose reacts to an invasion by viruses that cause infections
such as the common cold or flu by producing mucus and sending white blood cells
to the lining of the nose, which congest and swell the nasal passages. When
this swelling involves the adjacent mucous membranes of your sinuses, air and
mucus are trapped behind the narrowed openings of the sinuses. When your sinus
openings become too narrow, mucus cannot drain properly. This increase in mucus
sets up prime conditions for bacteria to multiply. Most healthy people harbor
bacteria, such as Streptococcus pneumoniae and Haemophilus influenzae, in their
upper respiratory tracts with no problems until the body's defenses are weakened
or drainage from the sinuses is blocked by a cold or other viral infection.
Thus, bacteria that may have been living harmlessly in your nose or throat can
multiply and invade your sinuses, causing an acute sinus infection. Sometimes,
fungal infections can cause acute sinusitis.
Although fungi are abundant in the environment, they usually are harmless to
healthy people, indicating that the human body has a natural resistance to them.
Fungi, such as Aspergillus, can cause serious illness in people whose immune
systems are not functioning properly. Some people with fungal sinusitis have
an allergic-type reaction to the fungi.
Chronic inflammation of the nasal passages also can lead to sinusitis.
If you have allergic rhinitis or hay fever, you can develop episodes of acute
sinusitis. Vasomotor rhinitis, caused by humidity, cold air, alcohol, perfumes,
and other environmental conditions, also may be complicated by sinus infections.
Acute sinusitis is much more common in some people than in the general population.
For example, sinusitis occurs more often in people who have reduced immune function
(such as those with immune deficiency diseases or HIV infection) and with abnormality
of mucus secretion or mucus movement (such as those with cystic fibrosis). What
causes chronic sinusitis? If you have asthma, an allergic disease, you may have
frequent episodes of chronic sinusitis. If you are allergic to airborne allergens,
such as dust, mold, and pollen, which trigger allergic rhinitis, you may develop
chronic sinusitis. In addition, people who are allergic to fungi can develop
a condition called "allergic fungal sinusitis."
If you are subject to getting chronic sinusitis, damp weather, especially in
northern temperate climates, or pollutants in the air and in buildings also
can affect you. Like acute sinusitis, you might develop chronic sinusitis if
you have an immune deficiency disease or an abnormality in the way mucus moves
through and from your respiratory system (e.g., immune deficiency, HIV infection,
and cystic fibrosis). In addition, if you have severe asthma, nasal polyps (small
growths in the nose), or a severe asthmatic response to aspirin and aspirin-like
medicines such as ibuprofen, you might have chronic sinusitis often.
How is sinusitis diagnosed?
Because your nose can get stuffy when you have a condition like the common cold,
you may confuse simple nasal congestion with sinusitis. A cold, however, usually
lasts about 7 to 14 days and disappears without treatment. Acute sinusitis often
lasts longer and typically causes more symptoms than just a cold. Your doctor
can diagnose sinusitis by listening to your symptoms, doing a physical examination,
and taking X-rays, and if necessary, an MRI or CT scan (magnetic resonance imaging
and computed tomography).
How is sinusitis treated?
After diagnosing sinusitis and identifying a possible cause, a doctor can suggest
treatments that will reduce your inflammation and relieve your symptoms. Acute
sinusitis If you have acute sinusitis, your doctor may recommend Decongestants
to reduce congestion Antibiotics to control a bacterial infection, if present
Pain relievers to reduce any pain You should, however, use over-the-counter
or prescription decongestant nose drops and sprays for only few days. If you
use these medicines for longer periods, they can lead to even more congestion
and swelling of your nasal passages.
If bacteria cause your sinusitis, antibiotics used along with a nasal or oral
decongestant will usually help. Your doctor can prescribe an antibiotic that
fights the type of bacteria most commonly associated with sinusitis. Many cases
of acute sinusitis will end without antibiotics. If you have allergic disease
along with infectious sinusitis, however, you may need medicine to relieve your
allergy symptoms. If you already have asthma then get sinusitis, you may experience
worsening of your asthma and should be in close touch with your doctor. In addition,
your doctor may prescribe a steroid nasal spray, along with other treatments,
to reduce your sinus congestion, swelling, and inflammation.
Chronic sinusitis
Doctors often find it difficult to treat chronic sinusitis successfully, realizing
that symptoms persist even after taking antibiotics for a long period. In general,
however, treating chronic sinusitis, such as with antibiotics and decongestants,
is similar to treating acute sinusitis. Some people with severe asthma have
dramatic improvement of their symptoms when their chronic sinusitis is treated
with antibiotics. Doctors commonly prescribe steroid nasal sprays to reduce
inflammation in chronic sinusitis. Although doctors occasionally prescribe them
to treat people with chronic sinusitis over a long period, they don't fully
understand the long-term safety of these medications, especially in children.
Therefore, doctors will consider whether the benefits outweigh any risks of
using steroid nasal sprays.
If you have severe chronic sinusitis, your doctor may prescribe oral steroids,
such as prednisone. Because oral steroids are powerful medicines and can have
significant side effects, you should take them only when other medicines have
not worked. Although home remedies cannot cure sinus infection, they might give
you some comfort. Inhaling steam from a vaporizer or a hot cup of water can
soothe inflamed sinus cavities. Saline nasal spray, which you can buy in a drug
store, can give relief.
Gentle heat applied over the inflamed area is comforting. When medical treatment
fails, surgery may be the only alternative for treating chronic sinusitis. Research
studies suggest that the vast majority of people who undergo surgery have fewer
symptoms and better quality of life. In children, problems often are eliminated
by removal of adenoids obstructing nasal-sinus passages. Adults who have had
allergic and infectious conditions over the years sometimes develop nasal polyps
that interfere with proper drainage.
Removal of these polyps and/or repair of a deviated septum to ensure an open
airway often provides considerable relief from sinus symptoms. The most common
surgery done today is functional endoscopic sinus surgery, in which the natural
openings from the sinuses are enlarged to allow drainage. This type of surgery
is less invasive than conventional sinus surgery, and serious complications
are rare.
How can I prevent sinusitis?
Although you cannot prevent all sinus disorders-any more than you can avoid
all colds or bacterial infections-you can do certain things to reduce the number
and severity of the attacks and possibly prevent acute sinusitis from becoming
chronic.
You may get some relief from your symptoms with a humidifier, particularly if
room air in your home is heated by a dry forced-air system. Air conditioners
help to provide an even temperature.
Electrostatic filters attached to heating and air conditioning equipment are
helpful in removing allergens from the air. If you are prone to getting sinus
disorders, especially if you have allergies, you should avoid cigarette smoke
and other air pollutants.
If your allergies inflame your nasal passages, you are more likely to have a
strong reaction to all irritants. If you suspect that your sinus inflammation
may be related to dust, mold, pollen, or food-or any of the hundreds of allergens
that can trigger an upper respiratory reaction-you should consult your doctor.
Your doctor can use various tests to determine whether you have an allergy and
its cause. This will help you and your doctor take appropriate steps to reduce
or limit your allergy symptoms.
Drinking alcohol also causes nasal and sinus membranes to swell. If you are
prone to sinusitis, it may be uncomfortable for you to swim in pools treated
with chlorine, since it irritates the lining of the nose and sinuses.
Divers often get sinus congestion and infection when water is forced into the
sinuses from the nasal passages. You may find that air travel poses a problem
if you are suffering from acute or chronic sinusitis. As air pressure in a plane
is reduced, pressure can build up in your head blocking your sinuses or eustachian
tubes in your ears. Therefore, you might feel discomfort in your sinus or middle
ear during the plane's ascent or descent. Some doctors recommend using decongestant
nose drops or inhalers before your flight to avoid this problem.
What research is going on?
Scientific studies have shown a close relationship between having allergic rhinitis
and chronic sinusitis. In fact, some studies state that up to 80 percent of
adults with chronic sinusitis also had allergic rhinitis. There is also an association
between asthma and sinusitis. Some researchers think that as many as 75 percent
of people with asthma also get sinusitis. The National Institute of Allergy
and Infectious Diseases (NIAID) conducts and supports research on allergic diseases
as well as bacteria and fungus that can cause sinusitis. This research is focused
on developing better treatments and ways to prevent these diseases. Scientists
supported by NIAID and other institutions are investigating whether chronic
sinusitis has genetic causes. They have found that the alterations in genes
which cause cystic fibrosis may also contribute to chronic sinusitis. This research
focus will give scientists new insights into the cause of the disease in some
people and points to new strategies for diagnosis and treatment. Another NIAID-supported
research study is trying to determine whether fungi may play a role in causing
many cases of chronic sinusitis. This research also will help scientists develop
better medicines to treat chronic sinusitis.
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